मंगलवार, 24 अक्तूबर 2017

Talcum powder's links to ovarian cancer: What it really means

Does talcum powder — powder that many have slathered on babies for generations -- really cause cancer?


वैज्ञानिक पहलू  :

टेलकम पाउडर जब प्रजनन अंगों के गिर्द छिड़का जाता है तब इसके सूक्ष्म कण योनि में सुगमता से जगह बना लेते हैं ,गर्भाशय गर्दन के पार ये न सिर्फ गर्भाशय तक आ जाते हैं अंडवाहिनी नलिकाओं (fallopian tubes )में भी प्रवेश ले लेते हैं।अण्ड़ाशय में ही पैठ पसर जाते हैं।  

आखिर फीमेल एग मैथुन के दौरान स्खलित स्पर्मेटे-जोआ से काम के प्रजनन क्षम स्पर्म्स (या शुक्राणओं )को एक अपार चुंबकीय बल की मानिंद अंदर खींच के ले जाता है बस इसे मौक़ा मिलने की देर होती है।बुनावट और संरचना ही ऐसी है वल्वा की यौनिक प्रणाली की। नारी का  प्रजनन तंत्र एक पेचीला लकिन नाज़ुक तंत्र या प्रणाली है . 

शिशुओं को जो डायपर पहनाया जाता है यह माँ के लिए ही सुविधा बनता है शिशु के लिए इससे ज्यादा वाहियात और कोई बात स्वास्थ्य विज्ञान के नज़रिये से हो नहीं सकती। ऊपर से तुर्रा ये के डायपर बदलते वक्त खुलकर पाउडर और छिड़क दिया जाता है आसपास । 

अब अगर आप किसी फंक्शन में हैं तो सारा सौदा मलमूत्र वहीँ  डायपर के अंदर ही पुट्रिफाई हो रहता है।

जन्म के समय कन्याएं अपने हिस्से के फीमेल एग्स लिए ही इस दुनिया में आती हैं ,जिनका प्रजनन क्षम उमर बनी रहने तक क्षय होता रहता है टेक आफ होता है यौवनारम्भ पर प्यूबर्टी पर।जब षोडशी रजस्वला हो जाती है मासिक चक्र की शुरुआत हो जाती है । मेनआरके कहा जाता है इस चरण को यानी मेंस्ट्रुअल साइकिल अब आरम्भ हो जाता है।  

कैंसर एवं  ,रोगविज्ञान के माहिरों ने कई मर्तबा कैंसर ग्रस्त अण्ड़ाशय -ऊतकों (Ovarian tissues )में टेलकम पाउडर के अल्पांश को बाकायदा देखा दर्ज़ किया है। यह कोई सुनी सुनाई बात नहीं है आँखन देखी  है। ऊतक जांच से ये सच्चाई सामने बार बार आयी  है। 

अलावा इसके पेल्विक लिम्फ नॉड्स (श्रोणि क्षेत्र की लसिका गांठों ,लसिका ग्रंथियों में भी इसकी व्याप्ति मिली है गर्ज़ ये के फेलोपियन ट्यूब्स से होता हुआ है आमाशय स्पेस में भी आया है टेलकम पाउडर । 

२०१३ में पहली मर्तबा एक अंडाशय कैंसर की जद में आई अमरीकी महिला ने एक नामचीन उपभोक्ता सामिग्री बनाने वाले अमरीकी निगम  को कचहरी में इसी वजह से घसीटा था जिन्होंने इसी कम्पनी का तैयार किया टेलकम पाउडर बरसों बरस इस्तेमाल किया था। 
फिलवक्त ऐसी ही बदनसीब कोई हज़ार अमरीकी महिलायें इस निगम के खिलाफ कानूनी कार्रवाई के लिए कतार बांधे कमर कसके खड़ी  हैं। 

स्त्री रोग और प्रसूति विज्ञान के माहिरों के अनुसार हर बरस कोई दस हज़ार अमरीकी महिलाएं टेलकम पाउडर के इस्तेमाल के चलते ओवेरियन कैंसर का शिकार हो रहीं हैं। 

कई अध्ययनों से इसकी पुष्टि हुई है अण्ड़ाशय कैंसर के खतरे का वजन ३३ फीसद बढ़ा हुआ हो सकता है इन अध्ययनों का यह साफ़ संकेत है। 

कमसे कम इतना तो हो- ये उपभोक्ता निगम तम्बाकू निगमों की तरह अपने उत्पाद पे एक चेतावनी ही ज़ारी करें -टेलकम पाउडर  का इस्तेमाल महिलाओं में एक ख़ास किस्म के कैंसर को बढ़ावा दे सकता है इस्तेमाल से पूर्व अपने हेल्थ केअर माहिर से पूँछें। 

संदर्भ -सामिग्री :

http://www.cnn.com/2016/05/03/opinions/talcum-powder-lawsuit-award-vox/index.html

विशेष :आंग्ल भाषा प्रेमियों के लिए मूल पाठ अंग्रेजी भाषा में भी दिया जा रहा है संदर्भ -सामिग्री सहित। 

There are more than 1,000 women lined up to sue Johnson & Johnson over just that: cancer diagnoses they attribute to the company's talcum powder products.

On Monday, a St. Louis jury ordered the company to pay $55 million to a South Dakota woman who had used talcum powder for years and has ovarian cancer.

So what's the big problem with a product millions of people have considered so safe they put it on babies during diaper change?
The theory is that talcum powder, when applied in the genital region, manages to work its way up through the vagina, the cervix, the uterus, the fallopian tubes and into the ovaries.
The female reproductive system has, after all, evolved to facilitate the upward mobility of sperm in order to fertilize eggs that have descended into the uterus, and the microscopic particles of talcum powder may well keep traveling all the way up.
Indeed, doctors have identified talc particles inside cancerous ovarian tissue. Talc has also been found in pelvic lymph nodes, indicating that it made it all the way out of the fallopian tubes and into the abdominal space.
In 2013, Deane Berg of Sioux Falls, South Dakota, was the first woman diagnosed with ovarian cancer to take on the medical and consumer products giant.
She came away without a dime awarded to her even though she won her suit; instead of awarding monetary damages the jury told Johnson & Johnson that it should affix a warning to its talc products like Johnson's Baby Powder and Shower to Shower, one that says the product could cause cancer.
And Berg's lawsuit laid historic legal groundwork: The company will now have to pay a combined $127 million in damages awarded in two cases by St. Louis juries this year if its appeals aren't successful.
In the Berg lawsuit, Brigham and Women's Hospital obstetrician and gynecologist Dr. Daniel Cramer testified to his opinion that upwards of 10,000 women a year are developing ovarian cancer in part due to their use of talcum powder.
Pathologist Dr. John Godleski, also at Brigham, found talc particles inside Berg's ovarian tumor tissue.
I don't have records from the two St. Louis cases where juries have penalized Johnson & Johnson with megamillion-dollar awards to the plaintiffs, but I'd expect those juries saw similar evidence to what Berg presented in 2013.
In fact, Cramer and his colleagues at Brigham just published a large study looking back at over 2,000 women diagnosed with ovarian cancer and comparing their use of talcum powder with that of a similar group of women who didn't have ovarian cancer.
In showing a strong link between talc use and ovarian cancer, a 33% higher risk overall, the Brigham group specifically faulted another large study published in 2014 that didn't identify a risk. That study, Cramer wrote, didn't look at premenopausal women who seem to be at higher risk, and didn't properly weigh the role of estrogen use, which seems to be a necessary ingredient in upping the risk for ovarian cancer in postmenopausal women.
The medical debate over whether talcum powder causes ovarian cancer goes back many decades, and the attorneys in these cases are demonstrating, through internal documents they've subpoenaed, that Johnson & Johnson knew about this research.
They allege that Johnson & Johnson is akin to the tobacco companies that knew about research linking smoking to lung cancer but kept this information from the public and fought off attempts to regulate their product.
I don't think Johnson & Johnson deserves quite the opprobrium we reserve for the tobacco companies, since conflicting research did exist, but they and companies like them are setting themselves up for these kinds of lawsuits if they're not open and transparent with consumers.
A smarter approach would have been to acknowledge the worrisome research studies in their consumer literature, on their websites, and to have flagged customers somehow on their product labeling to review this material with their doctors and decide for themselves whether and how to use the products.
But it's not all Johnson & Johnson's responsibility. Federal agencies like the Food and Drug Administration, the Centers for Disease Control and Prevention and the Consumer Products Safety Commission need the authority and the funding to keep up with reported and published adverse effects of all consumer products, and actively weigh when mandatory warnings are necessary.
Companies should welcome the federal agencies taking off some of the load -- Johnson & Johnson could have shared some of its liability with such an agency by regularly checking in about how it should act, or what warning it should issue, in light of recent research.
We have a problem when it falls to trial juries to weigh the scientific data on a given product against a particular medical case and decide whether a company should be adding warning labels, or paying out large sums in the hopes the companies will learn a lesson.
That's one way to get the job done, but it's after the fact, it's messy, and it's prone to error and excess. We can expect that appeals will significantly reduce these headline-grabbing jury awards.
Reference:http://www.cnn.com/2016/05/03/opinions/talcum-powder-lawsuit-award-vox/index.html


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