बुधवार, 4 जून 2014

Anti-diabetic drug could slow aging process: study

सुबह  एक  समाचार आलइंडिआ रेडिओ से सुना :डायबिटीस के इलाज़ में इस्तेमाल होने वाली एक दवा 

बुढ़ापे को आगे खिसका सकती है हेल्दी एजिंग की ओर  ले जाती है तब बड़ी सुखद अनुभूति हुई। एक साइंस 

कम्युनिकेटर के रूप में मैं स्वयं कितने  ही मधुमेह रोगियों को इलाज़ के लिए ले जाने की पहल कर चुका हूँ। 

अक्सर  इस लाइलाज बने रहने वाली बीमारी की गंभीरता को लोग समझ नहीं पाते हैं कहते हैं हमें तो कोई 

दिक्कत ही नहीं है दवा खाएंगे तो फिर दवा खाने की आदत पड़ जाएगी। हमारे इस डिफेन्स स्टेशन में कई 

दूकानदार ऐसे ही हैं। हमने उन्हें फट जाकर बतलाया :दवा नियमित खाने की एक वजह और मिल गई है 

आपको  मेटफॉर्मिन् जो मधुमेह के प्रबंधन में इस्तेमाल होने वाली आम दवा है (आजकल कई अन्य दवाओं के 

साथ कॉम्बो में भी दी जा रही है)हेल्दी एजिंग की ओर  ले जाती है आप इसका इस्तेमाल किसी भी सूरत में बंद 

न करें। अपने डायबेटेलॉजिस्ट की हर बात माने ,पढ़िए इसी आशय की यह पूरी रिपोर्ट :

Anti-diabetic drug could slow aging process: study

Anti-diabetic drug could be used to slow aging
A drug used to treat diabetes could be used to slow aging. ©Mike Flippo/shutterstock.com

A recent study published in the journal Proceedings of the National Academy of Sciences indicates that the 

popular anti-diabetic drug metformin may slow aging and could even increase lifespan.

The findings represent a shift in beliefs about antioxidants, thought to neutralize the effects of highly reactive 

oxygen molecules produced by the mitochondria during cell-to-cell energy transfer.

Due to their potential to disrupt normal cell functioning as well as damage proteins and DNA, these 

molecules are thought to ignite the aging process.

The research shows that a small amount can be beneficial and that metformin, which allows just a small 

release of reactive oxygen molecules, could soon play a key role in healthy aging.

"As long as the amount of harmful oxygen molecules released in the cell remains small, it has a positive long-

term effect on the cell. Cells use the reactive oxygen particles to their advantage before they can do any 

damage," explains Belgian doctoral researcher and study leader Wouter De Haes. "Metformin causes a 


increase in the number of harmful oxygen molecules. We found that this makes cells stronger and extends 

their healthy lifespan."

The study involved experiments on a short-lived species of roundworm called Caenorhabditis elegans, so 


effects of the drug on humans are yet to be confirmed.

"As they age, the worms get smaller, wrinkle up and become less mobile. But worms treated with metformin 

show very limited size loss and no wrinkling. They not only age slower, but they also stay healthier longer," 

says Wouter De Haes. "While we should be careful not to over-extrapolate our findings to humans, the 


is promising as a foundation for future research."

For a long time, the food and cosmetics industries have pumped their products full of antioxidants to claim 


anti-aging component.

While the study does not dispute the anti-aging qualities of antioxidants it suggests that they could neutralize 

the effects of metformin.

A study published in the European Journal of Cancer, meanwhile, suggests that metformin could one day be 

used to treat and prevent cancer.